ncRNA name | hsa-miR-29 |
ncRNA Category | miRNA |
Disease name | choroidal neovascularization (CNV) |
Species | Homo sapiens |
Tissues/Cell_line | human RPE cell line ARPE-19; umbilical vein endothelial cell line EA hy926; human embryonic kidney cell line HEK293 |
Methods | immunohistochemistry, transfection, Western blot, qRT-PCR, luciferase reporter assay |
Expression pattern | down-regulated |
Functional description | NFκB activation inhibits miR-29s, which may contribute to angiogenesis by up-regulating the MMP-2 protein level in RPE cells. |
PubMed ID | 24886609 |
Year | 2014 |
Title | Roles of NFκB-miR-29s-MMP-2 circuitry in experimental choroidal neovascularization. |
Drug-related ncRNA | NO |
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